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    Submission
    7 weeks left
    Evaluation
    Starts Nov 2
    Closed
    Aug 1, 2027

    Announcement of Opportunity for Human Research in Concordia Station, Antarctica (AO-2026-Concordia)

    ESA, IPEV and PNRA are soliciting for biomedical and psychological experiments to be implemented in Concordia Station in Antarctica

    ESA, IPEV and PNRA are soliciting for biomedical and psychological experiments to be implemented at the Concordia station in Antarctica (AO-2026-Concordia).

    Note: Science teams interested in applying are invited to a Q&A virtual meeting that will be held during the Announcement of Opportunity phase to support prospective applicants in preparing their proposals and to address any questions they may have. Details of the meeting can be found below under [Section  4]. 

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    1. INTRODUCTION

    The European Space Agency’s (ESA) Exploration Science element is a key component of the Explore2040 strategy, supporting scientific research that advances both space exploration and fundamental scientific knowledge. The programme combines exploration-focused science, which addresses the knowledge and capabilities required for future human exploration missions, with exploration-enabled science, which leverages exploration platforms and infrastructure to enable research across a broad range of disciplines. 

    Exploration Science encompasses activities across multiple destinations and environments, ranging from the microgravity conditions of low Earth orbit to the lunar surface and, ultimately, Mars. The programme supports scientific investigations conducted aboard the International Space Station, future commercial low Earth orbit platforms, lunar orbital and surface infrastructures, and other exploration missions, providing access to unique research environments that cannot be replicated on Earth. 

    Exploration Science is guided by European principles of scientific excellence, international collaboration, responsible exploration, and open science. It aims to generate knowledge that enhances our understanding of the universe, supports the development of future exploration capabilities, and contributes to addressing challenges that benefit society on Earth. In parallel, Exploration Science seeks to inspire future generations and strengthen Europe's role in the global exploration endeavour. 

    Through its portfolio of missions, facilities, and research opportunities, ESA’s Exploration Science element enables the scientific community to address fundamental questions in the physical, life, and planetary sciences while supporting the long-term goals of human and robotic exploration beyond Earth. 

    Crewed missions to the Moon and Mars will add an entirely new dimension to human spaceflight. Psychological and physiological challenges will surpass anything humans have undertaken before. In this context, extreme terrestrial environments play a key role in enabling the study of human adaptation to extreme and remote conditions. A winterover in an Antarctic research stations has several aspects in common with future spaceflight missions. The high level of isolation, confinement, limited medical support, and the extreme environment create a unique opportunity for the study of human adaptation.

    2. DETAILS OF THE PLATFORM

    Figure 1. Concordia Station, Antarctica

    Concordia Station is a French-Italian research facility jointly operated and funded by the French Polar Institute (IPEV) and the Italian Antarctic Programme (PNRA). It is one of the most isolated Antarctic research bases, situated 1000 kilometres from the Antarctic coast on the East Antarctic High Plateau. Concordia can only be accessed during the summer season. Summer personnel leave in late January, and from then on, a crew of 12-16 scientists and technicians spends 10 months living and working in the station in complete isolation.

    Quick facts:

    Location:              Dome C, 3233 meters above sea level (with air pressure equivalent to almost 4000

                                   meters at the equator)

    Summer season: November – late January

                                   Station reachable by plane and traverse

                                  ~80 people on site

                                   Mean temperature -35°C

                                   ~100 days of polar day

    Winterover:          February – end of October

                                   No evacuation possible during winter

                                   Polar night from May – August (~100 days)

                                   12-16 people on site

                                   Mean temperature -60°C (down to -80°C)

                                  ~100 days of polar night

    Winterover crew:  predominantly French and Italian

                                    aged between ~20-60 yrs old

                                    technicians and scientists

                                    predominantly male

    Since 2005, IPEV, PNRA and ESA have worked together to implement biomedical and psychological research experiments, and test innovative technologies relevant to space exploration in Concordia Station. Each year, a Research Medical Doctor is selected to be part of the crew and to conduct ESA experiments on site.  While conducting research in Antarctica is fundamental to improving the well-being and health of astronauts, it can also deliver tangible benefits on Earth by enhancing the living and working conditions of people in remote, isolated, or otherwise extreme environments.

    Please note that Concordia does not provide a controlled analogue space mission setting. It is an operational station and the crewmembers, each of which has their dedicated role, are volunteers for the ESA experiments. Nevertheless, these real-world operational conditions make Concordia a unique and highly relevant platform for space exploration research.   

    The crew consists of about 50% technical support (mechanic, plumber, electrotechnician, IT, etc.), and 50% scientists from various fields (glaciology, astronomy, atmospheric physics, computer science, etc.), one of which is a Research MD dedicated to the ESA experiments. A surgeon and a cook are also part of the crew. A station leader from within the crew is appointed by IPEV and PNRA before departure for Antarctica. This person then functions as the mission commander.  Food and supplies are delivered during the summer season and meals (lunch and dinner) are prepared by the station’s cook. There is no strict diet. During the winterover, each crewmember has their private bedroom, all other facilities are shared. The station is equipped with a gym (various devices such as a treadmill, ergometer, climbing wall, weights), however exercise is voluntary and done in the crewmember’s free time. The station has only very limited access to the internet. 

    Investigators will not be in direct contact with the participants, but represented by the Research MD. Should a higher number of participants be required, experiments can run over several winterover seasons. 

    It is important to design experiments with this setup in mind to ensure participant compliance. Please also keep in mind that while the winterover starts in February, the crew may arrive as early as November at the station. Summer is a very busy time and scheduling experiments right after arrival is not impossible, but may be challenging. Furthermore, the summer season does not provide the same level of isolation and confinement as the winterover period, and data collected during this phase may therefore be less representative of an extreme environment. 

    For specific questions, please use the Q&A form as well as the virtual Q&A session (see Section 4).

    More information on Concordia station can be found at http://www.esa.int/concordia, as well as on the French and Italian Antarctic national programmes' websites ( https://institut-polaire.fr/en/ and https://www.pnra.aq/). See Annex 1 for additional details.

     Figure 2. Antarctica and the location of Concordia Station

    3. DESCRIPTION OF THE OPPORTUNITY

    The Steering Committee of Concordia (representing the Italian and French National Antarctic programmes) and ESA release this joint AO for biomedical and psychological experiments to be implemented in Concordia Station, to address human research questions that are relevant to ESA’s Exploration Science, enabling human missions to the Moon, Mars, and beyond.  

    The research questions listed below are intended as examples and are not exhaustive. Investigators are encouraged to propose innovative approaches and additional research questions that align with the overall objectives of this AO. For more detailed examples of relevant research questions, please see Annex 8.

    a. Behavioural Health, Mental Well-Being and Cognitive Performance

    Long-duration exploration missions will expose crews to prolonged isolation, confinement, operational demands, and restricted social interactions. Understanding the factors that influence psychological well-being, resilience, and performance is a key research priority.

       b. Team Functioning and Social Dynamics

      Future exploration missions will depend on small autonomous teams operating in isolated and resource-constrained environments. Understanding the factors that promote effective teamwork and crew cohesion is, therefore, essential.

      c. Human Physiology, Sleep and Circadian Adaptation

      The unique environmental conditions at Concordia provide opportunities to investigate physiological adaptation during prolonged residence in extreme environments.

      d. Physical Activity, Nutrition and Metabolic Health

      Maintaining physical capacity, metabolic health, and adequate nutrition will be critical for future exploration missions.

      e. Integrated Health Monitoring and Predictive Health

      Future exploration missions will require reliable and resource-efficient approaches for monitoring health and performance.

      f. Immunology, Microbiome and Host–Environment Interactions

      Long-duration residence in isolated environments may affect immune function, microbial ecosystems, and host–environment interactions. Understanding these processes is important for maintaining health and operational readiness during future exploration missions.

      g. Medical Autonomy and Healthcare in Remote Environments

      Future exploration missions will require increasing levels of medical autonomy due to communication delays, limited resources, and the absence of rapid evacuation options.

      h. Cross-Cutting Topic: Countermeasure Development and Validation

      Identification, development, validation, and operational assessment of countermeasures aimed at maintaining or improving health, well-being, performance, and operational capability.  Countermeasures may address one or multiple domains. 

      Isolation Standard Measures

      During the winterover seasons, Isolation Standard Measures (ISM, Annex 7) will be collected. Applying science teams can request access to these data to supplement their own research.

      The use of ISM data is encouraged where these measurements complement or can substitute for elements of your experimental protocol. However, please note that the full implementation of the ISM package is subject to feasibility and resource constraints, and not all measures can be guaranteed for every season. Therefore, if you intend to rely on specific ISM measures, please clearly indicate whether they are to be used as primary measures or secondary measures (e.g., as covariates), so that appropriate workarounds can be explored should these measures become unavailable.

      Baseline data collection

      An opportunity to collect baseline data collection is organised by ESA once before departure to Concordia (roughly 6 weeks in advance) and once after return from Concordia (roughly 6 months after returning). This is done at :envihab, Cologne (DE). Specifics might differ for each winterover season and will be discussed in advance of the season with the selected science teams. Collecting data outside these opportunities will not be organised by ESA.

      4. SCHEDULE OF THE AO

       The schedule for this Announcement of Opportunity is as follows:

      • Launch of Announcement of Opportunity: 10 July 2026
      • Q&A virtual session: 14 September 2026 at 15:00 - 16:30 CEST (meeting will end earlier if all questions are answered)
        • Link to meeting:

          Microsoft Teams: Join the meeting here

          Meeting ID: 369 701 766 556 358

          Passcode: fU9M9PB6

      • Link to Q&A Submission Form: Ask your question here
      • Submission deadline for full proposals:  2 November 2026 at 23:59 CET
      • Implementation: Not earlier than Winterover 2029
        • Please note that preparations (science and operational requirements definition, crew training, hardware shipment, etc.) for winterover 2029 will start in early 2028.

      If you have any further questions, feel free to contact the Campaign Manager using the following channels: 

      • Please post questions that require a timely response in OSIP
      • In preparation for the virtual Q&A session, you may submit questions in advance through the form linked in Section 4
      • Detailed discussions and questions will be handled in the meeting
      • Please refrain from sending emails

      5. APPLICATION PROCESS

      All components of the proposal submission must be provided in English, including the content of the online submission form and any uploaded attachments or supporting documents. 

      Kindly submit your completed proposal and Experimental Data Sheet (see templates in Annex 2 and 3) by clicking on the Submit Your Idea button below. Complete all sections of the submission form as per guidelines outlined in the call, upload all required attachments, and complete any additional information as required.  

      Full project proposals must be accompanied by a completed Experimental Data Sheet (Annex 3). This document is essential for evaluating the scientific and technical feasibility of the proposed experiment and to ensure alignment with mission constraints.  

      ESA will organise a Q&A virtual meeting to present the details of the call and the associated facility, and to address any questions from prospective proposers. This session is intended to support interested teams in preparing strong and well-informed proposals. Please see Section 4. Schedule of the AO for details on this session.

      If you have any further technical questions during submission, feel free to contact the Campaign Manager using the channels mentioned in Section 4.

      Privacy Notice 

      Please ensure that all team members complete and sign the Privacy Consent Form (Annex 4) and include them as part of the proposal submission.

      6. DATA RIGHTS AND MANAGEMENT

      Please ensure you are familiar with the data rights, data ownership, and the data management responsibilities applicable to the datasets a selected science team will acquire as part of the campaign as described in the ESA HRE Data Policy (see Annex 5).

      Publications and Acknowledgement

      Any publication of the results generated in the context of this announcement of opportunity shall acknowledge the sponsorship of the study by the European Space Agency, IPEV, and PNRA. ESA’s Scientists are encouraged to publish their results in open‑access journals. Scientists are also encouraged to notify ESA about their publication at explorationscience@esa.int 

      Support of Education and Outreach

      The activities covered in this research announcement provide an opportunity for the European Space Agency to engage the public and offer opportunities for education and outreach. Science Teams are encouraged to promote and communicate their investigations to a wide audience (general public, colleagues, involvement of students, social media) and to support the European Space Agency in the event of organized press conferences, social media events, educational activities, publications, etc. 

       

      ELIGIBILITY 

      The scientific institution for which the coordinator of a proposal is working must be located in one of the ESA member or associated member states that contribute to the European Exploration Envelope Programme (E3P): Austria, Belgium, Canada, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Latvia, Luxemburg, Netherlands, Norway, Poland, Portugal, Romania, Slovenia, Spain, Sweden, Switzerland, United Kingdom 

      Scientists representing institutions from other ESA member states may participate in proposals as team members. Scientists representing institutions from ESA Member States that do not contribute to the E3P Programme and scientists from other European countries having a cooperation agreement with ESA (e.g. Cyprus, Malta, Slovakia) are encouraged to enquire with their national space organization about the conditions for their participation in proposals to ESA. 

      Applicants must confirm that they have informed their national space agency/delegation prior to submitting their proposal. This step is essential to explore potential national funding procedures, timelines, and likelihood of support, and to identify alternative funding sources if necessary. Please note that non-compliance could result in ineligibility for selection/funding. The Points of Contacts for each national space agency can be found in the Attachments section of this page (Annex 6). 

      In addition, the science team listed in a proposal (including the Principal Investigator and all co-investigators) must not include any individual who is a member of the team of the associated study facility responsible for implementing the core protocol. Proposals that include such individuals will be considered ineligible.

      IMPLEMENTATION OF THE SELECTED EXPERIMENTS 

      After proposal selection (see section below on evaluation criteria), implementation is foreseen to start as of winterover season 2029. Preparation activities (science and operational requirements definition, crew training, hardware shipment, etc.) will start earlier (see section 4). Please note:  

      • Not all selected projects will be implemented within the same winterover season. Due to operational and resource constraints, implementation will be phased, and projects will be introduced progressively over multiple winterover seasons. Therefore, while some projects may begin in the earlier campaigns, others may be scheduled for subsequent seasons.  

      • ESA, IPEV and PNRA reserve the right to select only a part of a proposed project if this portion is still of high scientific merit. The applicant will be given the choice to accept or decline such a partial opportunity. 

      • ESA, IPEV and PNRA strives to ensure a balanced and complementary portfolio of scientific investigations. As such, if two or more proposals address similar problems and/or adopt similar approaches, it may be requested that the science teams consolidate specific parts of their projects into a single project and work as one team. 

      • Lastly, if a high volume of proposals is received, the selection will be made to fit within the available resources of the platform. In such cases, even proposals that meet the minimum evaluation criteria may not be selected to advance to the definition phase.  

      All selected experiments will be coordinated on site by a Research Medical Doctor (Research MD). TheResearch Medical Doctor is selected and appointed each year and he/she will be responsible for coordinating and implementing all experiments during a given winterover season. Science teams shall train the ESA Research MD in advance before the departure to Concordia.  

      It shall be noted that ESA provides access to Concordia crew members during the pre-BDC (approximately 6 weeks before departure), in-mission, and post-BDC (approximately 6 months after return) phases only. Access to crewmembers outside these activities (e.g., immediately after return from Antarctica), will not be organized by ESA.  

      ESA does not financially support the work of selected experimenters, it only offers access to the platform and pre-scheduled BDC meetings. Any additional expenses related to the proposed work of an experimenter, including costs for travel (e.g., to meetings) and subsistence, are considered investigator-related costs, which are not sponsored by ESA. Funding from national agencies / organisations, universities, or other institutions is required to cover investigator-related costs and implementation.  

      Investigators who need to visit Concordia Station to support their investigation must provide a strong justification. Subject to approval by the Concordia Steering Committee, travel and accommodation from the port of Departure - Hobart (Australia) or Christchurch (New Zealand) - will be covered by IPEV and PNRA, but the travel from their own country to the port of departure and return will not be financially supported. 

      After completion of the experiment, a report to ESA and the Concordia Steering Committee which highlights findings, namely those that could be of operational interest for the French and Italian National Antarctic Programmes by increasing the quality of life at the Station, shall be submitted. This report will remain confidential. 

      Contribution to ESA’s HRE Exploration Biobank  

      ESA is establishing an HRE Exploration Biobank to enable future research opportunities by preserving biological samples collected during exploration-related studies. ESAmaycollect targeted samples for long-term storage within the biobank. In addition, science teams with selected proposals for implementation in Concordia campaigns will be asked  to indicate any residual sample material generated through their experiments that may be made available for long-term storage in the ESA HRE Exploration Biobank. Thedetailed process, including documentation requirements, ethical considerations, and applicable standards, will be communicated at a later stage during the study preparation phase. Formal agreements, where applicable, will also be addressed at that time. Please note that any contribution of residual samples will require participant consent and inclusion in the relevant ethical approvals prior to implementation.

      ARCHIVING THE DATA 

      After completion of the whole experiment, the Science Team will be granted an exclusive access period to the data for the purpose of analysis and publication. In addition, the Science Team will be obliged to deposit the experimental data obtained during their project in the ESA database for long-term archiving. To support this archiving, each selected science team will be requested to fill and prepare a Data Blank Book (see example in Annex 10), a document outlining the data products, data details (i.e., extension), and if applicable, metadata. 

      Programme-compliant proposals submitted in response to this AO will undergo a scientific merit (peer) review. The peer review panel will consist of independent scientific experts with the appropriate background to evaluate the proposals; reviewers will be selected by ESA in coordination with IPEV and PNRA. Only those proposals most highly rated in the scientific merit review process will undergo the additional review for feasibility. 

      The criteria that will be applied for the evaluation of the proposals are: 

      • Significance (50%): Does the proposed study address an important problem or challenge indicated within AO? Are there a clear, well-grounded and elaborated scientific justification and motivation provided in the proposal? Does the proposed research lead to an advance which is incremental or paradigm-shifting?
      • Approach (35%)
        • Design & Feasibility (15%): conceptual framework, integration with aims, platform justification, scientific risk and mitigation, data management plan.  
        • Methodological Rigour (20%): completeness and quality of the methodological aspects (Mth. 1-7): is the primary outcome specifically expressed, istheprimary analysis appropriate and yields an effect estimate (not just a p-value), isthe power calculation grounded in the expected effect, are confounders and mediators handled. 
      • Knowledge translation and Future Impact (15%): Will the results of the research provide a benefit to Earth or for space exploration? Will the results (or other aspects related to the experiment) have a sustained impact on research in the future?
      • Personnel and Environment (Pass/fail): Are there sufficient and appropriate personnel dedicated to the project?

      Each proposal will receive a scientific merit score between 0 and 100 points. The proposals will receive one of the following marks:

      • Outstanding: 100 - 91 points 
      • Excellent: 90 - 81 points 
      • Very Good: 80 - 71 points 
      • Good: 70-61 points
      • Fair: 60 - 51 points 
      • Inadequate: 50 - 0 points 

      Only proposals receiving a scientific merit score of “Excellent” or higher (score of 81 or higher) will proceed in the evaluation process. Furthermore, a minimum score of "VeryGood" or higher (score of 71 or higher) is needed for each sub-criterion. Thisistoensure the selection of proposals that are balanced and scoring well across all sub-criteria composing the science merit score.

      Additional criteria 

      In addition, the following criteria will be applied: 

      • Research Platform Relevance (Pass/fail): Can the objectives and protocol be achieved within the capabilities and constraints of the platform? Is the requested platform mandatory for this proposed study? Can other laboratory means be used without/before going to this platform? Given the limited availability and constraints of this platform, it is important that only experiments which cannot be done elsewhere use this platform. Therefore, if a proposal cannot demonstrate a clear need for the chosen research platform, it will not be recommended for selection. 
      • Programmatic Assessment (Pass/fail): To ensure that the programme can be implemented in a defined time period, the number and complexity of the projects in the research pool should match the resources and capabilities of the programme. For this reason, ESA shall only select as many projects as can be realistically implemented in a reasonable timeframe, taking into account the existing research pool and work plan. At the same time, to ensure that the programme is inclusive and provides equal opportunities, ESA will encourage the submission of proposals demonstrating balanced collaborations among the scientific and technological communities from all ESA Member States. 
      • Technical Feasibility Assessment (Pass/fail): Each proposal will undergo a preliminary pass/fail technical and operational feasibility assessment, either prior to or in parallel with the peer review process. This assessment aims to determine the proposal's compatibility with the capabilities of the chosen research platform, evaluate the technical, operational, and development complexity of the required hardware and activities, and identify the resources necessary for successful project implementation. Ifrequired, a feasibility assessment will be conducted in consultation with the COC (Concordia Operational Committee (IPEV/PNRA)). 

      Following approval of the proposal, the proposers will be informed of the outcome of the review. This will include the report of the scientific and technical review with overall scoring. 

      The results of the selection will be final and not open to appeal. A positive selection may still require adjustments to enhance scientific return and optimize feasibility.

      Note: If a high volume of proposals is received, the selection will be fit within the available resources of the Concordia winter over campaigns. In such cases, even proposals that meet the minimum evaluation criteria may not be selected to advance to the definition phase. In addition to overall evaluation scores, ESA also strives to ensure a balanced and complementary portfolio of scientific investigations. As such, final selection may take into account thematic diversity and complementarity across proposals. In cases where two or more high-scoring proposals show significant overlap, ESA may recommend that science teams consider collaboration or merging of protocols to strengthen the overall scientific return.

      Do you need help?

      Campaign Manager - Carmen Possnig, Science Management support

      Thank you for your interest in our Announcement of Opportunity for Human Research in Concordia, Antarctica (AO-2026-Concordia). My name is Carmen and I am the ESA Science Coordinator for this OSIP campaign and AO. You can ask questions in the discussion section below your idea, via the Q&A submission form, or in the virtual Q&A session. We will do our best to respond to your questions and help you with the submission of your idea.

      Background Information

      Innovation Area

      Human and Robotic Exploration

      ESA’s Terrae Novae exploration programme is leading Europe’s human journey into the Solar System using robots as precursors and scouts. Exploring space is about travelling farther and coming back with new experiences and knowledge to help us on Earth. Humankind will benefit from the new discoveries, ambitions, science, inspiration and challenges. 

      Help advance human space exploration!

      We appreciate all input. Even rough ideas can fuel a discussion and help to ideate. Help us to improve by submitting your own ideas to this campaign.